World’s most efficient known free radical scavenger is C60 fullerene.
- C60 fullerenes possess a large amount of conjugated double bonds and low lying lowest unoccupied molecular orbital which can easily take up an electron from an attack of an oxygen radical.
- 34 oxygen radicals have been added onto a single C60 molecule. The fullerene can react with many superoxides without being consumed.
- C60 fullerene derivatives are rapidly absorbed by tissues and excreted through urinary tract; low to no toxicity in vitro and in vivo in studies.
- C60 fullerene is able to cross the blood-brain barrier.